Publications
Relevent Peer-Reviewed Publications
Zhou J, Satheesan S, Li H, Weinberg M.S., Morris K.V., Burnett, J.C., and Rossi, J.R. Cell-Specific RNA Aptamer against Human CCR5 Specifically Targets HIV-1 Susceptible Cells and Inhibits HIV-1 Infectivity. Chemistry and Biology, chembiol.2015.01.005, 2015. PMID: 25754473
Morris KV. The theory of RNA-mediated gene evolution. Epigenetics. 2015 Jan 2;10(1):1-5. Epub 2015 Jan 27. PMID:25581873
K.V. Morris and J. S. Mattick. The Rise of Regulatory RNA. Nature Reviews Genetics 2014 Apr 29. doi: 10.1038/nrg3722. PMID:24776770
Saayman, S., Ackley, A., Turner, A.W., Famiglietti, M., Bosque, A., Clemson, M., Planelles, V., and Morris KV. An HIV-Encoded Antisense Long Noncoding RNA Epigenetically Regulates Viral Transcription. Molecular Therapy. 2014 Feb 28. doi: 10.1038/mt.2014.29. NIHMSID#569381
Ackley A, Lenox A, Stapleton K, Knowling S, Lu T, Sabir K.S., Vogt P.K.,* and Morris K.V. An algorithm for generating small RNAs capable of epigenetically modulating transcriptional gene silencing and activation in human cells. Molecular Therapy—Nucleic Acids (2013) 2, e1; doi:10.1038/mtna.2013.33
Johnsson P, Ackley A, Vidarsdottir L, Lui WO, Corcoran M, Grandér D, Morris KV. A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells. Nature Structural Molecular Biology, (2013) Feb 24, PMID 23435381
Knowling S, Stapleton K, Turner AM, Uhlmann E, Lehmann T, Vollmer J and Morris KV. Chemically Modified Oligonucleotides Modulate an Epigenetically Varied and Transient Form of Transcription Silencing of HIV-1 in Human Cells. Molecular Therapy Nucleic Acids (2012) 1, e16; doi:10.1038/mtna. 2012.8.
Morris KV. Lamarck and the Missing Lnc. The Scientist , October 1, 2012, invited editorial (view here).
Turner AM, Ackley AM, Matrone MA, Morris KV. Characterization of an HIV-targeted transcriptional gene-silencing RNA in primary cells. Hum Gene Ther. 2012 May;23(5):473-83. PMID:22122263
Morris KV. The emerging role of RNA in the regulation of gene transcription in human cells. Seminars in Cell and Developmental Biology, 2011 Feb 16, PMID:21333746
Hawkins, P.G., Santoso, S., Adams, C., Anest, V., and Morris, K.V. (2009). Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells. Nucleic Acids Res.
Morris KV. Non-coding RNAs, epigenetic memory, and the passage of information to progeny. RNA Biol. 2009 Jul 5;6(3). Perspective. PMID: 19305164/NIHMSID: 146963
Morris KV. Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cells. Epigenetics. 2009 Jul 17;4(5). Perspective. PMID: 19633414/NIHMSID: 146957
Relevent Books
RNA and the regulation of Gene expression; a hidden layer of complexity. Editor K.V. Morris. Horizon press. March 2008, ISBN 978-1-904455-25-7.
Non-coding RNAs and Epigenetic Regulation of Gene Expression; Drivers of Natural Selection. Editor K.V. Morris. Caister Academic Press. ISBN 978-1-904455-94-3.
Interviews
Kevin V. Morris on Transcriptional Gene Silencing